Stratifin (SFN) (N-Term) Peptide
SFN
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all 14-3-3 sigma/SFN (SFN) products
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
- 蛋白结构域
- N-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- IEQKSNEEGS EEKGPEVREY REKVETELQG VCDTVLGLLD SHLIKEAGDA
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-SFN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- 14-3-3 sigma/SFN (SFN) (Stratifin (SFN))
- 背景
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SFN is a p53-regulated inhibitor of G2/M progression. It is an adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. It binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. It may also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
Alias Symbols: SFN,HME1,
Protein Size: 248 - 基因ID
- 2810
- NCBI登录号
- NP_006133
- UniProt
- P31947
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