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Chromobox Homolog 7 (CBX7) Peptide

CBX7 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5512656
发货至: 中国
  • 抗原 See all CBX7 products
    CBX7 (Chromobox Homolog 7 (CBX7))
    宿主
    资源
    • 3
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    产品特性
    This is a synthetic peptide designed for use in combination with anti-CBX7 antibody (Catalog #: ARP74429_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    CBX7 (Chromobox Homolog 7 (CBX7))
    别名
    1600014J01Rik Peptide, AI851678 Peptide, D15Ertd417e Peptide, zgc:110152 Peptide, chromobox 7 Peptide, chromobox homolog 7a Peptide, CBX7 Peptide, Cbx7 Peptide, cbx7a Peptide
    背景
    CBX7 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.

    Protein Size: 251
    分子量
    27 kDa
    基因ID
    23492
    NCBI登录号
    NP_783640
    UniProt
    O95931
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