Chromobox Homolog 7 (CBX7) Peptide
CBX7
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN5512656
发货至:
中国
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Contact Info
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Quick Overview for Chromobox Homolog 7 (CBX7) Peptide (ABIN5512656)
抗原
CBX7
(Chromobox Homolog 7 (CBX7))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CBX7 antibody (Catalog #: ARP74429_P050) made by Aviva Systems Biology. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CBX7 (Chromobox Homolog 7 (CBX7))
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背景
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CBX7 is a component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Promotes histone H3 trimethylation at 'Lys-9' (H3K9me3). Binds to trimethylated lysine residues in histones, and possibly also other proteins. Regulator of cellular lifespan by maintaining the repression of CDKN2A, but not by inducing telomerase activity.
Protein Size: 251 -
分子量
- 27 kDa
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基因ID
- 23492
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NCBI登录号
- NP_783640
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UniProt
- O95931
抗原
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