NLR Family, Pyrin Domain Containing 12 (NLRP12) (N-Term) Peptide
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Quick Overview for NLR Family, Pyrin Domain Containing 12 (NLRP12) (N-Term) Peptide (ABIN5512640)
抗原
宿主
资源
应用范围
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蛋白结构域
- N-Term
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序列
- LEVSLVTPRK DPQETYRDYV RRKFRLMEDR NARLGECVNL SHRYTRLLLV
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产品特性
- This is a synthetic peptide designed for use in combination with anti-NLRP12 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NLRP12 (NLR Family, Pyrin Domain Containing 12 (NLRP12))
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背景
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This gene encodes a member of the CATERPILLER family of cytoplasmic proteins. The encoded protein, which contains an N-terminal pyrin domain, a NACHT domain, a NACHT-associated domain, and a C-terminus leucine-rich repeat region, functions as an attenuating factor of inflammation by suppressing inflammatory responses in activated monocytes. Mutations in this gene cause familial cold autoinflammatory syndrome type 2. Alternative splicing results in multiple transcript variants.
Alias Symbols: NLRP12,NALP12,PYPAF7,RNO,
Protein Size: 1061 -
基因ID
- 91662
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NCBI登录号
- NP_653288
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UniProt
- P59046
抗原
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