Chitotriosidase (CHIT1) (C-Term) Peptide
CHIT1
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN5512621
发货至:
中国
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Quick Overview for Chitotriosidase (CHIT1) (C-Term) Peptide (ABIN5512621)
抗原
Chitotriosidase 1 (CHIT1)
(Chitotriosidase (CHIT1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- GTPELEVPKP GQPSEPEHGP SPGQDTFCQG KADGLYPNPR ERSSFYSCAA
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产品特性
- This is a synthetic peptide designed for use in combination with anti- CHIT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Chitotriosidase 1 (CHIT1) (Chitotriosidase (CHIT1))
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背景
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Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene.
Alias Symbols: CHI3, CHIT, CHITD
Protein Size: 466 -
基因ID
- 1118
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NCBI登录号
- NM_001256125, NP_001243054
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UniProt
- Q13231
抗原
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