Methyl-CpG Binding Domain Protein 4 (MBD4) (Middle Region) Peptide
MBD4
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all MBD4 products
- MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- TSLKPEDFDF TVLSKRGIKS RYKDCSMAAL TSHLQNQSNN SNWNLRTRSK
- 产品特性
- This is a synthetic peptide designed for use in combination with anti- MBD4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))
- 背景
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The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Alias Symbols: MED1
Protein Size: 580 - 基因ID
- 8930
- NCBI登录号
- NM_001276270, NP_001263199
- UniProt
- O95243
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