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Methyl-CpG Binding Domain Protein 4 (MBD4) (Middle Region) Peptide

MBD4 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5512590
发货至: 中国

Quick Overview for Methyl-CpG Binding Domain Protein 4 (MBD4) (Middle Region) Peptide (ABIN5512590)

抗原

MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))

宿主

资源

  • 2
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    Middle Region

    序列

    TSLKPEDFDF TVLSKRGIKS RYKDCSMAAL TSHLQNQSNN SNWNLRTRSK

    产品特性

    This is a synthetic peptide designed for use in combination with anti- MBD4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    MBD4 (Methyl-CpG Binding Domain Protein 4 (MBD4))

    背景

    The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

    Alias Symbols: MED1

    Protein Size: 580

    基因ID

    8930

    NCBI登录号

    NM_001276270, NP_001263199

    UniProt

    O95243
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