Ubiquitin Specific Peptidase 19 (USP19) (Middle Region) Peptide
USP19
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all USP19 products
- USP19 (Ubiquitin Specific Peptidase 19 (USP19))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- SQFTGYAQHD AQEFMAFLLD GLHEDLNRIQ NKPYTETVDS DGRPDEVVAE
- 产品特性
- This is a synthetic peptide designed for use in combination with anti- USP19 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- USP19 (Ubiquitin Specific Peptidase 19 (USP19))
- 别名
- wu:fc26a05 Peptide, si:dkey-32e6.9 Peptide, USP19 Peptide, MGC145127 Peptide, ZMYND9 Peptide, 8430421I07Rik Peptide, AI047774 Peptide, Zmynd9 Peptide, ubiquitin specific peptidase 19 Peptide, universal stress protein Peptide, ubiquitin carboxyl-terminal hydrolase 19 Peptide, usp19 Peptide, USP19 Peptide, RR_RS18085 Peptide, PTRG_09611 Peptide, Usp19 Peptide
- 背景
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Deubiquitinating enzyme that regulates the degradation of various proteins. Deubiquitinates and prevents proteasomal degradation of RNF123 which in turn stimulates CDKN1B ubiquitin-dependent degradation thereby playing a role in cell proliferation. Involved in decreased protein synthesis in atrophying skeletal muscle. Modulates transcription of major myofibrillar proteins. Also involved in turnover of endoplasmic-reticulum-associated degradation (ERAD) substrates. Regulates the stability of BIRC2/c-IAP1 and BIRC3/c-IAP2 by preventing their ubiquitination. Required for cells to mount an appropriate response to hypoxia and rescues HIF1A from degradation in a non-catalytic manner. Plays an important role in 17 beta-estradiol (E2)-inhibited myogenesis. Decreases the levels of ubiquitinated proteins during skeletal muscle formation and acts to repress myogenesis. Exhibits a preference towards 'Lys-63'-linked Ubiquitin chains.
Alias Symbols: ZMYND9
Protein Size: 1419 - 基因ID
- 10869
- NCBI登录号
- NM_001199160, NP_001186089
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