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Runt-Related Transcription Factor 3 (RUNX3) (C-Term) Peptide

RUNX3 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5512454
发货至: 中国

Quick Overview for Runt-Related Transcription Factor 3 (RUNX3) (C-Term) Peptide (ABIN5512454)

抗原

RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

宿主

资源

  • 5
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    C-Term

    序列

    PQNQSGPFQA NPSPYHLYYG TSSGSYQFSM VAGSSSGGDR SPTRMLASCT

    产品特性

    This is a synthetic peptide designed for use in combination with anti-RUNX3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    RUNX3 (Runt-Related Transcription Factor 3 (RUNX3))

    背景

    This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

    Alias Symbols: RUNX3,AML2, CBFA3, PEBP2A3,

    Protein Size: 415

    基因ID

    864

    UniProt

    Q13761
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