Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (Middle Region) Peptide
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Quick Overview for Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10) (Middle Region) Peptide (ABIN5512377)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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序列
- VAGEMGQNEP DQGGQRGVII NTASVAAFEG QVGQAAYSAS KGGIVGMTLP
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产品特性
- This is a synthetic peptide designed for use in combination with anti- HSD17B10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HSD17B10 (Hydroxysteroid (17-Beta) Dehydrogenase 10 (HSD17B10))
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背景
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This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Alias Symbols: ABAD, CAMR, ERAB, HCD2, MHBD, HADH2, MRPP2, MRX17, MRX31, SCHAD, MRXS10, SDR5C1, 17b-HSD10, DUPXp11.22
Protein Size: 261 -
基因ID
- 3028
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NCBI登录号
- NM_001037811, NP_001032900
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UniProt
- Q99714
抗原
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