Histamine N-Methyltransferase (HNMT) (Middle Region) Peptide
HNMT
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all HNMT products
- HNMT (Histamine N-Methyltransferase (HNMT))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- STMDISDCFI DGNENGDLLW DFLTETCNFN ATAPPDLRAE LGKDLQEPEF
- 产品特性
- This is a synthetic peptide designed for use in combination with anti- HNMT Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- HNMT (Histamine N-Methyltransferase (HNMT))
- 背景
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In mammals, histamine is metabolized by two major pathways: N(tau)-methylation via histamine N-methyltransferase and oxidative deamination via diamine oxidase. This gene encodes the first enzyme which is found in the cytosol and uses S-adenosyl-L-methionine as the methyl donor. In the mammalian brain, the neurotransmitter activity of histamine is controlled by N(tau)-methylation as diamine oxidase is not found in the central nervous system. A common genetic polymorphism affects the activity levels of this gene product in red blood cells. Multiple alternatively spliced transcript variants that encode different proteins have been found for this gene.
Alias Symbols: HMT, HNMT-S1, HNMT-S2
Protein Size: 292 - 基因ID
- 3176
- NCBI登录号
- NM_001024074, NP_001019245
- UniProt
- P50135
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