Death-Domain Associated Protein (DAXX) (N-Term) Peptide
DAXX
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN5512286
发货至:
中国
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Quick Overview for Death-Domain Associated Protein (DAXX) (N-Term) Peptide (ABIN5512286)
抗原
DAXX
(Death-Domain Associated Protein (DAXX))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- KLNLAPAATT SNEPSGNNPP THLSLDPTNA ENTASQSPRT RGSRRQIQRL
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产品特性
- This is a synthetic peptide designed for use in combination with anti-DAXX Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DAXX (Death-Domain Associated Protein (DAXX))
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背景
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This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants.
Alias Symbols: Name=DAXX,
Protein Size: 740 -
基因ID
- 1616
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NCBI登录号
- NP_001341
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UniProt
- Q9UER7
抗原
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