Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (Middle Region) Peptide
DMTF1
适用: 人
宿主: 合成
BP, WB
Quick Overview for Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) (Middle Region) Peptide (ABIN5512274)
抗原
DMP1 (DMTF1)
(Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- FSRSTGKGGD DKDDDEDDSG DDTFGDDDSG PGPKDRQEGG NSRLGSDEDS
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产品特性
- This is a synthetic peptide designed for use in combination with anti- DMP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1) peptide
DMTF1 适用: 人 宿主: 合成 BP, Imm
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- DMP1 (DMTF1) (Cyclin D Binding Myb-Like Transcription Factor 1 (DMTF1))
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背景
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Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: ARHP, ARHR, DMP-1
Protein Size: 497 -
基因ID
- 1758
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NCBI登录号
- NM_001079911, NP_001073380
抗原
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