Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2) (N-Term) Peptide
BATF2
适用: 人
宿主: 合成
BP, WB
Quick Overview for Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2) (N-Term) Peptide (ABIN5512169)
抗原
BATF2
(Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- CGGNGLLTQT DPKEQQRQLK KQKNRAAAQR SRQKHTDKAD ALHQQHESLE
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产品特性
- This is a synthetic peptide designed for use in combination with anti-BATF2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- BATF2 (Basic Leucine Zipper Transcription Factor, ATF-Like 2 (BATF2))
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背景
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BATF2 is a AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, it participates in the differentiation of CD8(+) thymic conventional dendritic cells in the immune system. It acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (By similarity). It selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. It possibly acts by interfering with AP-1 binding to CYR61 promoter.
Alias Symbols: BATF2,
Protein Size: 274 -
基因ID
- 116071
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UniProt
- Q8N1L9
抗原
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