Aminolevulinate Dehydratase (ALAD) (Middle Region) Peptide
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Quick Overview for Aminolevulinate Dehydratase (ALAD) (Middle Region) Peptide (ABIN5512124)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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序列
- VPSRVPKDER GSAADSEESP AIEAIHLLRK TFPNLLVACD VCLCPYTSHG
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产品特性
- This is a synthetic peptide designed for use in combination with anti-ALAD Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ALAD (Aminolevulinate Dehydratase (ALAD))
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背景
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The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 Molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway, zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Alias Symbols: PBGS, ALADH
Protein Size: 330 -
基因ID
- 210
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NCBI登录号
- NM_000031, NP_000022
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UniProt
- P13716
抗原
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