Cold Inducible RNA Binding Protein (CIRBP) (Middle Region) Peptide
CIRBP
适用: 人
宿主: 合成
BP, WB
Quick Overview for Cold Inducible RNA Binding Protein (CIRBP) (Middle Region) Peptide (ABIN5512043)
抗原
CIRBP
(Cold Inducible RNA Binding Protein (CIRBP))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- SVDGRQIRVD QAGKSSDNRS RGYRGGSAGG RGFFRGGRGR GRGFSRGGGD
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CIRBP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CIRBP (Cold Inducible RNA Binding Protein (CIRBP))
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背景
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CIRBP is a cold-inducible mRNA binding protein that plays a protective role in the genotoxic stress response by stabilizing transcripts of genes involved in cell survival. It acts as a translational activator. Seems to play an essential role in cold- induced suppression of cell proliferation. It binds specifically to the 3'-untranslated regions (3'-UTRs) of stress-responsive transcripts RPA2 and TXN. It acts as a translational repressor (By similarity). Promotes assembly of stress granules (SGs), when overexpressed.
Alias Symbols: CIRBP,A18HNRNP,CIRP,
Protein Size: 172 -
基因ID
- 1153
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NCBI登录号
- NP_001271
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UniProt
- Q14011
抗原
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