Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1) (N-Term) Peptide
GAD1
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN5511873
发货至:
中国
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Contact Info
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Quick Overview for Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1) (N-Term) Peptide (ABIN5511873)
抗原
GAD (GAD1)
(Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- CGFLQRTNSL EEKSRLVSAF KERQSSKNLL SCENSDRDAR FRRTETDFSN
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产品特性
- This is a synthetic peptide designed for use in combination with anti-GAD1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- GAD (GAD1) (Glutamate Decarboxylase 1 (Brain, 67kDa) (GAD1))
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背景
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This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
Alias Symbols: GAD, SCP, CPSQ1
Protein Size: 594 -
基因ID
- 2571
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NCBI登录号
- NM_000817, NP_000808
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UniProt
- Q99259
抗原
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