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APOBEC1 Complementation Factor (A1CF) (N-Term) Peptide

A1CF 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5511770
发货至: 中国

Quick Overview for APOBEC1 Complementation Factor (A1CF) (N-Term) Peptide (ABIN5511770)

抗原

A1CF (APOBEC1 Complementation Factor (A1CF))

宿主

资源

  • 4
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    N-Term

    序列

    LGTCPEPEAS MSTAIPGLKK GNNALQSIIL QTLLEKENGQ RKYGGPPPGW

    产品特性

    This is a synthetic peptide designed for use in combination with anti-A1CF Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    A1CF (APOBEC1 Complementation Factor (A1CF))

    背景

    Mammalian apolipoprotein B mRNA undergoes site-specific C to U deamination, which is mediated by a multi-component enzyme complex containing a minimal core composed of APOBEC-1 and a complementation factor encoded by this gene. A1CF has three non-identical RNA recognition motifs and belongs to the hnRNP R family of RNA-binding proteins. It has been proposed that this complementation factor functions as an RNA-binding subunit and docks APOBEC-1 to deaminate the upstream cytidine. Studies suggest that the protein may also be involved in other RNA editing or RNA processing events. Alternative splicing occurs at this locus and three full-length transcript variants, encoding three distinct isoforms, have been described. Additional splicing has been observed but the full-length nature of these variants has not been determined.

    Protein Size: 659

    基因ID

    29974
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