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Transcription Factor E3 (TFE3) (Middle Region) Peptide

TFE3 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5511608
发货至: 中国

Quick Overview for Transcription Factor E3 (TFE3) (Middle Region) Peptide (ABIN5511608)

抗原

TFE3 (Transcription Factor E3 (TFE3))

宿主

资源

  • 5
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    Middle Region

    序列

    IRKLQKEQQR SKDLESRQRS LEQANRSLQL RIQELELQAQ IHGLPVPPTP

    产品特性

    This is a synthetic peptide designed for use in combination with anti-TFE3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    TFE3 (Transcription Factor E3 (TFE3))

    背景

    This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants.

    Alias Symbols: TFEA, RCCP2, RCCX1, bHLHe33

    Protein Size: 575

    基因ID

    7030

    NCBI登录号

    NM_001282142, NP_001269071

    UniProt

    P19532
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