Thyroid Peroxidase (TPO) (N-Term) Peptide
TPO
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN5511606
发货至:
中国
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Contact Info
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Quick Overview for Thyroid Peroxidase (TPO) (N-Term) Peptide (ABIN5511606)
抗原
Thyroperoxidase (TPO)
(Thyroid Peroxidase (TPO))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- GASNTALARW LPPVYEDGFS QPRGWNPGFL YNGFPLPPVR EVTRHVIQVS
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产品特性
- This is a synthetic peptide designed for use in combination with anti-TPO Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
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背景
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This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.
Protein Size: 611 -
基因ID
- 7173
抗原
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