Splicing Factor 3b, Subunit 3, 130kDa (SF3B3) (C-Term) Peptide
SF3B3
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all SF3B3 products
- SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
- 蛋白结构域
- C-Term
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- LPPNTNDEVD EDPTGNKALW DRGLLNGASQ KAEVIMNYHV GETVLSLQKT
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-SF3B3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- SF3B3 (Splicing Factor 3b, Subunit 3, 130kDa (SF3B3))
- 背景
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This gene encodes subunit 3 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 3 has also been identified as a component of the STAGA (SPT3-TAF(II)31-GCN5L acetylase) transcription coactivator-HAT (histone acetyltransferase) complex, and the TFTC (TATA-binding-protein-free TAF(II)-containing complex). These complexes may function in chromatin modification, transcription, splicing, and DNA repair.
Alias Symbols: SF3B3,KIAA0017,SAP130,
Protein Size: 1217 - 基因ID
- 23450
- NCBI登录号
- NP_036558
- UniProt
- Q15393
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