Nibrin (NBN) (Middle Region) Peptide
NBN
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all Nibrin (NBN) products
- Nibrin (NBN)
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- TGLKTTTPGP SLSQGVSVDE KLMPSAPVNT TTYVADTESE QADTWDLSER
- 产品特性
- This is a synthetic peptide designed for use in combination with anti-NBN Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- Nibrin (NBN)
- 别名
- NBN Peptide, AT-V1 Peptide, AT-V2 Peptide, ATV Peptide, NBS Peptide, NBS1 Peptide, P95 Peptide, Nbs1 Peptide, im:6911679 Peptide, zgc:194152 Peptide, nibrin Peptide, NBN Peptide, nbn Peptide, Nbn Peptide
- 背景
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Mutations in this gene are associated with Nijmegen breakage syndrome, an autosomal recessive chromosomal instability syndrome characterized by microcephaly, growth retardation, immunodeficiency, and cancer predisposition. The encoded protein is a member of the MRE11/RAD50 double-strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double-strand break repair and DNA damage-induced checkpoint activation.
Protein Size: 754 - 基因ID
- 4683
- UniProt
- O60934
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