Nuclear Receptor Binding Factor 2 (NRBF2) (Middle Region) Peptide
NRBF2
适用: 人
宿主: 合成
BP, WB
Quick Overview for Nuclear Receptor Binding Factor 2 (NRBF2) (Middle Region) Peptide (ABIN5511398)
抗原
NRBF2
(Nuclear Receptor Binding Factor 2 (NRBF2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- QLLLIQERWK RAQREERLKA QQNTDKDAAA HLQTSHKPSA EDAEGQSPLS
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产品特性
- This is a synthetic peptide designed for use in combination with anti- NRBF2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- NRBF2 (Nuclear Receptor Binding Factor 2 (NRBF2))
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背景
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May modulate transcriptional activation by target nuclear receptors. Can act as transcriptional activator (in vitro).Involved in starvation-induced autophagy probably by its association with PI3K complex I (PI3KC3-C1). However, effects has been described variably. Involved in the induction of starvation-induced autophagy. Stabilzes PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3. Proposed to negatively regulate basal and starvation-induced autophagy and to inhibit PIK3C3 activity by modulating interactions in PI3KC3-C1. May be involved in autophagosome biogenesis. May play a role in neural progenitor cell survival during differentiation.
Alias Symbols: COPR, COPR1, COPR2, NRBF-2
Protein Size: 287 -
基因ID
- 29982
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NCBI登录号
- NM_001282405, NP_110386
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UniProt
- Q96F24
抗原
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