MyoD Family Inhibitor (MDFI) (Middle Region) Peptide
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Quick Overview for MyoD Family Inhibitor (MDFI) (Middle Region) Peptide (ABIN5511381)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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序列
- AVTCQPQGNP LGCTPLLPND SGHPSELGGT RRAGNGALGG PKAHRKLQTH
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产品特性
- This is a synthetic peptide designed for use in combination with anti-MDFI Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- MDFI (MyoD Family Inhibitor (MDFI))
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背景
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This protein is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with myogenic factor function by masking nuclear localization signals and preventing DNA binding. Knockout mouse studies show defects in the formation of vertebrae and ribs that also involve cartilage formation in these structures.
Alias Symbols: MDFI,
Protein Size: 246 -
基因ID
- 4188
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NCBI登录号
- NP_005577
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UniProt
- Q99750
抗原
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