Histone Deacetylase 3 (HDAC3) (C-Term) Peptide
HDAC3
适用: 人
宿主: 合成
BP, WB
Quick Overview for Histone Deacetylase 3 (HDAC3) (C-Term) Peptide (ABIN5511258)
抗原
HDAC3
(Histone Deacetylase 3 (HDAC3))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- VQIHDVPADL LTYDRTDEAD AEERGPEENY SRPEAPNEFY DGDHDNDKES
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产品特性
- This is a synthetic peptide designed for use in combination with anti- HDAC3 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- HDAC3 (Histone Deacetylase 3 (HDAC3))
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背景
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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene.
Alias Symbols: HD3, RPD3, RPD3-2
Protein Size: 428 -
基因ID
- 8841
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NCBI登录号
- NM_003883, NP_003874
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UniProt
- O15379
抗原
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