Huntingtin Associated Protein 1 (HAP1) (Middle Region) Peptide
HAP1
适用: 人
宿主: 合成
BP, WB
Quick Overview for Huntingtin Associated Protein 1 (HAP1) (Middle Region) Peptide (ABIN5511254)
抗原
HAP1
(Huntingtin Associated Protein 1 (HAP1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
-
-
蛋白结构域
- Middle Region
-
序列
- ETLPGFQETL AEELRTSLRR MISDPVYFME RNYEMPRGDT SSLRYDFRYS
-
产品特性
- This is a synthetic peptide designed for use in combination with anti- HAP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
-
-
Huntingtin Associated Protein 1 (HAP1) peptide
HAP1 适用: 小鼠, 大鼠 宿主: 合成 BP, Imm
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
状态
- Lyophilized
-
溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
-
储存条件
- -20 °C
-
储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
-
-
- HAP1 (Huntingtin Associated Protein 1 (HAP1))
-
背景
-
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: HLP, HAP2, HIP5, hHLP1
Protein Size: 671 -
基因ID
- 9001
-
NCBI登录号
- NM_001079870, NP_001073339
-
UniProt
- P54257
抗原
-
You are here:
