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Huntingtin Associated Protein 1 (HAP1) (Middle Region) Peptide

HAP1 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5511253
发货至: 中国
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Quick Overview for Huntingtin Associated Protein 1 (HAP1) (Middle Region) Peptide (ABIN5511253)

抗原

HAP1 (Huntingtin Associated Protein 1 (HAP1))

宿主

资源

  • 5
合成

应用范围

Blocking Peptide (BP), Western Blotting (WB)
  • 蛋白结构域

    Middle Region

    序列

    VPLETLPGFQ ETLAEELRTS LRRMISDPVY FMERNYEMPR GDTSSLRYDF

    产品特性

    This is a synthetic peptide designed for use in combination with HAP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    HAP1 (Huntingtin Associated Protein 1 (HAP1))

    背景

    Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.

    Alias Symbols: HLP, HAP2, HIP5, hHLP1

    Protein Size: 671

    基因ID

    9001

    NCBI登录号

    NM_001079870, NP_001073339

    UniProt

    P54257
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