Huntingtin Associated Protein 1 (HAP1) (Middle Region) Peptide
HAP1
适用: 人
宿主: 合成
BP, WB
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- 抗原 See all HAP1 products
- HAP1 (Huntingtin Associated Protein 1 (HAP1))
- 蛋白结构域
- Middle Region
- 宿主
- 人
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资源
- 合成
- 应用范围
- Blocking Peptide (BP), Western Blotting (WB)
- 序列
- VPLETLPGFQ ETLAEELRTS LRRMISDPVY FMERNYEMPR GDTSSLRYDF
- 产品特性
- This is a synthetic peptide designed for use in combination with HAP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Huntingtin Associated Protein 1 (HAP1) peptide
HAP1 适用: 小鼠, 大鼠 宿主: 合成 BP, Imm
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- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
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- 状态
- Lyophilized
- 溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
- 储存条件
- -20 °C
- 储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- 抗原
- HAP1 (Huntingtin Associated Protein 1 (HAP1))
- 背景
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Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with huntingtin, with two cytoskeletal proteins (dynactin and pericentriolar autoantigen protein 1), and with a hepatocyte growth factor-regulated tyrosine kinase substrate. The interactions with cytoskeletal proteins and a kinase substrate suggest a role for this protein in vesicular trafficking or organelle transport. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Alias Symbols: HLP, HAP2, HIP5, hHLP1
Protein Size: 671 - 基因ID
- 9001
- NCBI登录号
- NM_001079870, NP_001073339
- UniProt
- P54257
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