Polycomb Group Ring Finger 2 (PCGF2) (Middle Region) Peptide
PCGF2
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN5511130
发货至:
中国
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Quick Overview for Polycomb Group Ring Finger 2 (PCGF2) (Middle Region) Peptide (ABIN5511130)
抗原
PCGF2
(Polycomb Group Ring Finger 2 (PCGF2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- EQEKGALSDD EIVSLSIEFY EGARDRDEKK GPLENGDGDK EKTGVRFLRC
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产品特性
- This is a synthetic peptide designed for use in combination with anti-PCGF2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- PCGF2 (Polycomb Group Ring Finger 2 (PCGF2))
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背景
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The protein encoded by this gene contains a RING finger motif and is similar to the polycomb group (PcG) gene products. PcG gene products form complexes via protein-protein interaction and maintain the transcription repression of genes involved in embryogenesis, cell cycles, and tumorigenesis. This protein was shown to act as a negative regulator of transcription and has tumor suppressor activity. The expression of this gene was detected in various tumor cells, but is limited in neural organs in normal tissues. Knockout studies in mice suggested that this protein may negatively regulate the expression of different cytokines, chemokines, and chemokine receptors, and thus plays an important role in lymphocyte differentiation and migration, as well as in immune responses.
Alias Symbols: MEL-18, RNF110, ZNF144
Protein Size: 344 -
基因ID
- 7703
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NCBI登录号
- NM_007144, NP_009075
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UniProt
- P35227
抗原
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