Tripeptidyl Peptidase I (TPP1) (C-Term) Peptide
TPP1
适用: 人
宿主: 合成
BP, WB
Quick Overview for Tripeptidyl Peptidase I (TPP1) (C-Term) Peptide (ABIN5511099)
抗原
TPP1
(Tripeptidyl Peptidase I (TPP1))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- QHGAGLFDVT RGCHESCLDE EVEGQGFCSG PGWDPVTGWG TPNFPALLKT
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产品特性
- This is a synthetic peptide designed for use in combination with anti- TPP1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TPP1 (Tripeptidyl Peptidase I (TPP1))
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背景
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This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome.
Alias Symbols: CLN2, GIG1, LPIC, SCAR7, TPP-1
Protein Size: 563 -
基因ID
- 1200
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NCBI登录号
- NM_000391, NP_000382
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UniProt
- O14773
抗原
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