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Cathepsin F (CTSF) (C-Term) Peptide

CTSF 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN5511087
发货至: 中国
  • 抗原 See all Cathepsin F (CTSF) products
    Cathepsin F (CTSF)
    蛋白结构域
    C-Term
    宿主
    资源
    • 4
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    RPLCSPWLID HAVLLVGYGN RSDVPFWAIK NSWGTDWGEK GYYYLHRGSG
    产品特性
    This is a synthetic peptide designed for use in combination with anti- CTSF Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    Cathepsin F (CTSF)
    别名
    CTSF Peptide, MGC140519 Peptide, cb420 Peptide, sb:cb420 Peptide, zgc:153093 Peptide, LOC100101596 Peptide, Ctsf Peptide, ACYPI000376 Peptide, catf Peptide, CATSF Peptide, CLN13 Peptide, AI481912 Peptide, cathepsin F Peptide, cathepsin W Peptide, CTSF Peptide, ctsf Peptide, Ctsf Peptide, ctsw Peptide, Tsp_02382 Peptide
    背景
    Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W.

    Alias Symbols: CATSF, CLN13

    Protein Size: 484
    基因ID
    8722
    NCBI登录号
    NM_003793, NP_003784
    UniProt
    Q9UBX1
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