Integrin alpha-L (ITGAL) (Middle Region) Peptide
ITGAL
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN5511047
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for Integrin alpha-L (ITGAL) (Middle Region) Peptide (ABIN5511047)
抗原
ITGAL
(Integrin alpha-L (ITGAL))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- MSCTDFSFHF PVCVQDLISP INVSLNFSLW EEEGTPRDQR AQGKDIPPIL
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产品特性
- This is a synthetic peptide designed for use in combination with anti-ITGAL Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- ITGAL (Integrin alpha-L (ITGAL))
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背景
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ITGAL encodes the integrin alpha L chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form the integrin lymphocyte function-associated antigen-1 (LFA-1), which is expressed on all leukocytes. LFA-1 plays a central role in leukocyte intercellular adhesion through interactions with its ligands, ICAMs 1-3 (intercellular adhesion molecules 1 through 3), and also functions in lymphocyte costimulatory signaling. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CD11A, LFA-1, LFA1A
Protein Size: 1170 -
基因ID
- 3683
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NCBI登录号
- NM_001114380, NP_001107852
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UniProt
- P20701
抗原
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