Caspase Recruitment Domain Family, Member 11 (CARD11) (Middle Region) Peptide
CARD11
适用: 人
宿主: 合成
BP, WB
Quick Overview for Caspase Recruitment Domain Family, Member 11 (CARD11) (Middle Region) Peptide (ABIN5511030)
抗原
CARD11
(Caspase Recruitment Domain Family, Member 11 (CARD11))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- SPRLSRASFL FGQLLQFVSR SENKYKRMNS NERVRIISGS PLGSLARSSL
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CARD11 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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Caspase Recruitment Domain Family, Member 11 (CARD11) peptide
CARD11 适用: 人, 小鼠, Cow, 犬 宿主: 合成 BP, Imm
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- CARD11 (Caspase Recruitment Domain Family, Member 11 (CARD11))
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背景
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The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying a characteristic caspase-associated recruitment domain (CARD). This protein has a domain structure similar to that of CARD14 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this protein activated NF-kappaB and induced the phosphorylation of BCL10.
Alias Symbols: PPBL, BENTA, BIMP3, IMD11, CARMA1
Protein Size: 1171 -
基因ID
- 84433
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NCBI登录号
- NM_032415, NP_115791
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UniProt
- Q8TES3
抗原
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