A Kinase (PRKA) Anchor Protein 12 (AKAP12) (Middle Region) Peptide
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Quick Overview for A Kinase (PRKA) Anchor Protein 12 (AKAP12) (Middle Region) Peptide (ABIN5510916)
抗原
宿主
资源
应用范围
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蛋白结构域
- Middle Region
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序列
- MLSSQERMKV QGSPLKKLFT STGLKKLSGK KQKGKRGGGD EESGEHTQVP
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产品特性
- This is a synthetic peptide designed for use in combination with anti- AKAP12 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
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背景
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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
Alias Symbols: SSeCKS, AKAP250
Protein Size: 1684 -
基因ID
- 9590
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NCBI登录号
- NM_005100, NP_005091
抗原
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