(1 reference)-
- 抗原 See all beta Amyloid (Abeta) products
- beta Amyloid (Abeta) (Amyloid beta (Abeta))
- 蛋白结构域
- AA 25-35
- 纯度
- > 95 %
-
-
- 限制
- 仅限研究用
-
- 储存条件
- -20 °C
-
-
: "In vitro antiamyloidogenic properties of 1,4-naphthoquinones." in: Biochemical and biophysical research communications, Vol. 400, Issue 1, pp. 169-74, (2010) (PubMed).
-
: "In vitro antiamyloidogenic properties of 1,4-naphthoquinones." in: Biochemical and biophysical research communications, Vol. 400, Issue 1, pp. 169-74, (2010) (PubMed).
-
- 抗原
- beta Amyloid (Abeta) (Amyloid beta (Abeta))
- 背景
- Beta-amyloid protein (Abeta), a major component of senile plaques of Alzheimer's disease (AD) in the brain, causes elevation of the intracellular free Ca2+ level and the production of robust free radicals. Beta-amyloid 25-35 induced apoptosis, characterized by decreased cell viability, neuronal DNA condensation, and fragmentation, is associated with an increase in intracellular free Ca2+ level, the accumulation of reactive oxygen species (ROS), and the activation of caspase-3. All of these effects induced by beta-amyloid 25-35 are reversed by genistein.
- CAS-编号
- 131602-53-4
-
You are here:
