(1 reference)
产品编号 ABIN399149
发货至:
中国
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Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
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Beijing Economic Technological Development Area
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Quick Overview for Amyloid beta (Abeta) (AA 25-35) Peptide (ABIN399149)
抗原
beta Amyloid (Abeta)
(Amyloid beta (Abeta))
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蛋白结构域
- AA 25-35
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纯度
- > 95 %
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限制
- 仅限研究用
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储存条件
- -20 °C
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: "In vitro antiamyloidogenic properties of 1,4-naphthoquinones." in: Biochemical and biophysical research communications, Vol. 400, Issue 1, pp. 169-74, (2010) (PubMed).
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: "In vitro antiamyloidogenic properties of 1,4-naphthoquinones." in: Biochemical and biophysical research communications, Vol. 400, Issue 1, pp. 169-74, (2010) (PubMed).
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- beta Amyloid (Abeta) (Amyloid beta (Abeta))
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背景
- Beta-amyloid protein (Abeta), a major component of senile plaques of Alzheimer's disease (AD) in the brain, causes elevation of the intracellular free Ca2+ level and the production of robust free radicals. Beta-amyloid 25-35 induced apoptosis, characterized by decreased cell viability, neuronal DNA condensation, and fragmentation, is associated with an increase in intracellular free Ca2+ level, the accumulation of reactive oxygen species (ROS), and the activation of caspase-3. All of these effects induced by beta-amyloid 25-35 are reversed by genistein.
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CAS-编号
- 131602-53-4
抗原
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