Amyloid beta (Abeta) (AA 1-42) Peptide
Abeta
Quick Overview for Amyloid beta (Abeta) (AA 1-42) Peptide (ABIN399128)
抗原
beta Amyloid (Abeta)
(Amyloid beta (Abeta))
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蛋白结构域
- AA 1-42
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纯度
- > 95 %
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限制
- 仅限研究用
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储存条件
- -20 °C
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- beta Amyloid (Abeta) (Amyloid beta (Abeta))
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背景
- This peptide is well suited to the quantitative determination of A 42 peptide. Alzheimer's disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide (A), a 40- to 43- amino-acid peptide cleaved from amyloid precursor protein by secretase (BACE) and a putative (gamma) secretase. Increased release of the -onger forms-of A peptide, A 42 and A 43, which have a greater tendency to aggregate than A 40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alleles or may other, still undiscovered factors.
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CAS-编号
- 107761-42-2
抗原
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