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Amyloid beta (Abeta) (AA 1-42) Peptide

Abeta
产品编号 ABIN399128
发货至: 中国
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Quick Overview for Amyloid beta (Abeta) (AA 1-42) Peptide (ABIN399128)

抗原

beta Amyloid (Abeta) (Amyloid beta (Abeta))
  • 蛋白结构域

    AA 1-42

    纯度

    > 95 %
  • 限制

    仅限研究用
  • 储存条件

    -20 °C
  • 抗原

    beta Amyloid (Abeta) (Amyloid beta (Abeta))

    背景

    This peptide is well suited to the quantitative determination of A 42 peptide. Alzheimer's disease (AD) is characterized by the presence of extracellular plaques and intracellular neurofibrillary tangles (NFTs) in the brain. The major protein component of these plaques is beta amyloid peptide (A), a 40- to 43- amino-acid peptide cleaved from amyloid precursor protein by secretase (BACE) and a putative (gamma) secretase. Increased release of the -onger forms-of A peptide, A 42 and A 43, which have a greater tendency to aggregate than A 40, occurs in individuals expressing certain genetic mutations, expressing certain ApoE alleles or may other, still undiscovered factors.

    CAS-编号

    107761-42-2
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