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Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) Peptide

ALOX5AP 适用: 人 宿主: 兔 BP
产品编号 ABIN2763850
发货至: 中国
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Quick Overview for Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP) Peptide (ABIN2763850)

抗原

ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))

宿主

资源

  • 4

应用范围

Blocking Peptide (BP)
  • 限制

    仅限研究用
  • 储存条件

    -80 °C
  • 抗原

    ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP))

    背景

    Seems to be required for the activation of 5-LO (5-lipoxygenase). Could play an essential role in the transfer of arachidonic acid to 5-LO. Binds to MK-886, a compound that blocks the biosynthesis of leukotrienes. Genetic variations in FLAP may be a cause of susceptibility to ischemic stroke [MIM:601367], also known as cerebrovascular accident or cerebral infarction. A stroke is an acute neurologic event leading to death of neural tissue of the brain and resulting in loss of motor, sensory and/or cognitive function. Ischemic strokes, resulting from vascular occlusion, is considered to be a highly complex disease consisting of a group of heterogeneous disorders with multiple genetic and environmental risk factors.
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