Hepatitis C Virus Core Genotype-1 a recombinant protein Expression System: E.coli
纯化方法
Proprietary chromatographic technique
纯度
> 95 % pure
应用备注
Each Investigator should determine their own optimal working dilution for specific applications.
限制
仅限研究用
状态
Liquid
缓冲液
50 mM tris-HCl, pH 8.0, with 60 mM NaCl, 10 mM glutathione, 0.25 % sarkosil and 55 % glycerol.
注意事项
Avoid repeated freeze/thaw cycles.
储存条件
RT/-20 °C
抗原
Nucelocapsid Genoytpe 1A
物质类
Viral Protein
背景
HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae. HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6). Alternative Names: HCV protein, HCV Recombinant protein, Hep C protein, Hepatitis C protein, HCV Nucleocapsid Genoytpe 1A protein