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Splicing factor U2AF 26 kDa subunit (U2AF1L4) (N-Term) Peptide

U2AF1L4 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN2185358
发货至: 中国
  • 抗原 See all Splicing factor U2AF 26 kDa subunit (U2AF1L4) products
    Splicing factor U2AF 26 kDa subunit (U2AF1L4)
    蛋白结构域
    N-Term
    宿主
    资源
    • 2
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    KIGVCRHGDR CSRLHNKPTF SQTIVLLNLY RNPQNTAQTA DGSHCHVSDV
    产品特性
    This is a synthetic peptide designed for use in combination with anti-U2AF1L4 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    Splicing factor U2AF 26 kDa subunit (U2AF1L4)
    别名
    U2 small nuclear RNA auxiliary factor 1-like protein 3 Peptide, U2AF1-RS3 Peptide, U2AF1-like 4 Peptide, U2AF1-like protein 3 Peptide, U2AF1L3 Peptide, U2AF1L3V1 Peptide, U2AF1RS3 Peptide, U2af26 Peptide, AA407033 Peptide, AF419339 Peptide, AI451269 Peptide, AW553050 Peptide, TMEM149 Peptide, U2 small nuclear RNA auxiliary factor 1 like 4 Peptide, U2 small nuclear RNA auxiliary factor 1-like 4 Peptide, U2AF1L4 Peptide, U2af1l4 Peptide
    背景
    U2AF1L4 is a RNA-binding protein that function as a pre-mRNA splicing factor. It plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. It acts by enhancing the binding of U2AF2 to weak pyrimidine tracts and also participates in the regulation of alternative pre-mRNA splicing. It activates exon 5 skipping of PTPRC during T-cell activation, an event reversed by GFI1. U2AF1L4 binds to RNA at the AG dinucleotide at the 3'-splice site.

    Protein Size: 220
    分子量
    24 kDa
    基因ID
    199746
    UniProt
    Q8WU68
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