Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1) (C-Term) Peptide
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Quick Overview for Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1) (C-Term) Peptide (ABIN2185197)
抗原
宿主
资源
应用范围
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蛋白结构域
- C-Term
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序列
- LNVLLYETPR VPDNSLLEAT SRSRSQASPS EDEDTFELRD RVRRIHVKRY
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产品特性
- This is a synthetic peptide designed for use in combination with anti-Tnfaip1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- TNFAIP1 (Tumor Necrosis Factor, alpha-Induced Protein 1 (Endothelial) (TNFAIP1))
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背景
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Tnfaip1 is a substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD2) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration. Its interaction with RHOB may regulate apoptosis.
Alias Symbols: Edp1
Protein Size: 316 -
分子量
- 34 kDa
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基因ID
- 287543
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NCBI登录号
- NM_182950, NP_891995
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UniProt
- Q7TNY1
抗原
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