Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA) (C-Term) Peptide
FIGLA
适用: 人, 小鼠
宿主: 合成
BP, WB
Quick Overview for Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA) (C-Term) Peptide (ABIN2185022)
抗原
FIGLA
(Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA))
宿主
人, 小鼠
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- SSTRELLGNA TQPTSCASGL KKEEEGPWAY AGHSEPLYSY HQSTVPETRS
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产品特性
- This is a synthetic peptide designed for use in combination with anti-Figla Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- FIGLA (Folliculogenesis Specific Basic Helix-Loop-Helix (FIGLA))
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背景
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Figla is a germ-line specific transcription factor implicated in postnatal oocyte-specific gene expression. It plays a key regulatory role in the expression of multiple oocyte-specific genes, including those that initiate folliculogenesis and those that encode the zona pellucida (ZP1, ZP2 and ZP3) required for fertilization and early embryonic survival. It is essential for oocytes to survive and form primordial follicles. The persistence of FIGLA in adult females suggests that it may regulate additional pathways that are essential for normal ovarian development. Figla binds to the E-box (5'-CANNTG-3') of the ZPs (ZP1, ZP2, ZP3) promoters.
Alias Symbols: bHLHc8
Protein Size: 194 -
分子量
- 21 kDa
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基因ID
- 26910
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NCBI登录号
- NM_012013, NP_036143
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UniProt
- O55208
抗原
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