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Diacylglycerol O-Acyltransferase 1 (DGAT1) (N-Term) Peptide

DGAT1 适用: 人, 小鼠 宿主: 合成 BP, WB
产品编号 ABIN2184872
发货至: 中国
  • 抗原 See all DGAT1 products
    DGAT1 (Diacylglycerol O-Acyltransferase 1 (DGAT1))
    蛋白结构域
    N-Term
    宿主
    人, 小鼠
    资源
    • 4
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    HRLQDSLFSS DSGFSNYRGI LNWCVVMLIL SNARLFLENL IKYGILVDPI
    产品特性
    This is a synthetic peptide designed for use in combination with anti-Dgat1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    DGAT1 (Diacylglycerol O-Acyltransferase 1 (DGAT1))
    背景
    Dgat1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. It may be involved in VLDL (very low density lipoprotein) assembly. In liver, Dgat1 plays a role in esterifying exogenous fatty acids to glycerol. It functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.

    Alias Symbols: C75990, D15Ertd23e, Dgat

    Protein Size: 498
    分子量
    57 kDa
    基因ID
    13350
    NCBI登录号
    NM_010046, NP_034176
    UniProt
    Q9Z2A7
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