This is a synthetic peptide designed for use in combination with anti-RGS17 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
Optimal working dilution should be determined by the investigator.
限制
仅限研究用
状态
Lyophilized
溶解方式
Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
浓度
1 mg/mL
缓冲液
Final peptide concentration is 1 mg/mL in PBS.
注意事项
Avoid repeat freeze-thaw cycles.
储存条件
-20 °C
储存方法
For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
抗原
RGS17
(Regulator of G-Protein Signaling 17 (RGS17))
别名
RGS17 Peptide, zgc:92802 Peptide, MGC179306 Peptide, RGS-17 Peptide, RGSZ2 Peptide, hRGS17 Peptide, 6430507P11Rik Peptide, Rgsz2 Peptide, regulator of G protein signaling 17 Peptide, regulator of G-protein signaling 17 Peptide, RGS17 Peptide, Rgs17 Peptide, rgs17 Peptide
背景
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.