This is a synthetic peptide designed for use in combination with antiHENMT1 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
HENMT1 is a methyltransferase that adds a 2'Omethyl group at the 3'end of piRNAs, a class of 24 to 30 nucleotide RNAs that are generated by a Dicerindependent mechanism and are primarily derived from transposons and other repeated sequence elements. This probably protects the 3'end of piRNAs from uridylation activity and subsequent degradation. Stabilization of piRNAs is essential for gametogenesis.