Synovial Sarcoma, X Breakpoint 2 (SSX2) (Middle Region) Peptide
SSX2
适用: 人
宿主: 合成
BP, WB
Quick Overview for Synovial Sarcoma, X Breakpoint 2 (SSX2) (Middle Region) Peptide (ABIN2184613)
抗原
SSX2
(Synovial Sarcoma, X Breakpoint 2 (SSX2))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- Middle Region
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序列
- TFGRLQGISP KIMPKKPAEE G NDSEEVPEAS GPQNDGKELC PPGKPTTS
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产品特性
- This is a synthetic peptide designed for use in combination with anti-SSX2 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- SSX2 (Synovial Sarcoma, X Breakpoint 2 (SSX2))
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背景
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SSX2 belongs to the family of highly homologous synovial sarcoma X (SSX) breakpoint proteins. These proteins may function as transcriptional repressors. They are also capable of eliciting spontaneously humoral and cellular immune responses in cancer patients, and are potentially useful targets in cancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes have been involved in the t(X,18) translocation characteristically found in all synovial sarcomas. This translocation results in the fusion of the synovial sarcoma translocation gene on chromosome 18 to one of the SSX genes on chromosome X. The encoded hybrid proteins are probably responsible for transforming activity. Two transcript variants encoding distinct isoforms have been identified for this gene.
Alias Symbols: CT5.2a, HD21, HOM-MEL-40, SSX
Protein Size: 223 -
分子量
- 24 kDa
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基因ID
- 6757
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NCBI登录号
- NM_175698, NP_783629
抗原
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