GRB2-Related Adaptor Protein (GRAP) (N-Term) Peptide
GRAP
适用: 人
宿主: 合成
BP, WB
Quick Overview for GRB2-Related Adaptor Protein (GRAP) (N-Term) Peptide (ABIN2184413)
抗原
GRAP
(GRB2-Related Adaptor Protein (GRAP))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- N-Term
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序列
- SDELAFNKGD TLKILNMEDD QNWYKAELRG VEGFIPKNYI RVKPHPWYSG
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产品特性
- This is a synthetic peptide designed for use in combination with antiGRAP Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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GRB2-Related Adaptor Protein (GRAP) peptide
GRAP 适用: 人, 大鼠, Cow, 小鼠 宿主: 合成 BP, Imm
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at 20C. Avoid repeat freezethaw cycles.
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- GRAP (GRB2-Related Adaptor Protein (GRAP))
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背景
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This gene encodes a member of the GRB2/Sem5/Drk family and functions as a cytoplasmic signaling protein which contains an SH2 domain flanked by two SH3 domains. The SH2 domain interacts with ligandactivated receptors for stem cell factor and erythropoietin, and facilitates the formation of a stable complex with the BCRABL oncoprotein. This protein also associates with the Ras guanine nucleotide exchange factor SOS1 (son of sevenless homolog 1) through its Nterminal SH3 domain. In general, it couples signals from receptor and cytoplasmic tyrosine kinases to the Ras signaling pathway.
Alias Symbols: -
Protein Size: 217 -
分子量
- 25 kDa
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基因ID
- 10750
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NCBI登录号
- NM_006613, NP_006604
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UniProt
- Q13588
抗原
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