Unc-13 Homolog D (UNC13D) (C-Term) Peptide
UNC13D
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN2184174
发货至:
中国
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Contact Info
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Quick Overview for Unc-13 Homolog D (UNC13D) (C-Term) Peptide (ABIN2184174)
抗原
UNC13D
(Unc-13 Homolog D (UNC13D))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- SGSEEPGEVP QTRLPLTYPA PNGDPILQLL EGRKGDREAQ VFVRLRRHRA
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产品特性
- This is a synthetic peptide designed for use in combination with anti-UNC13D Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- UNC13D (Unc-13 Homolog D (UNC13D))
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背景
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This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Alias Symbols: FHL3, HLH3, HPLH3, Munc13-4
Protein Size: 1090 -
分子量
- 119 kDa
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基因ID
- 201294
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NCBI登录号
- NM_199242, NP_954712
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UniProt
- Q70J99
抗原
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