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Corticotropin Releasing Hormone (CRH) (C-Term) Peptide

CRH 适用: 人 宿主: 合成 WB, BP
产品编号 ABIN2184150
发货至: 中国
  • 抗原 See all CRH products
    CRH (Corticotropin Releasing Hormone (CRH))
    蛋白结构域
    C-Term
    宿主
    资源
    • 10
    合成
    应用范围
    Western Blotting (WB), Blocking Peptide (BP)
    序列
    GGHQEAPERE RRSEEPPISL DLTFHLLREV LEMARAEQLA QQAHSNRKLM
    产品特性
    This is a synthetic peptide designed for use in combination with anti-CRH Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    CRH (Corticotropin Releasing Hormone (CRH))
    别名
    CRF Peptide, Gm1347 Peptide, crf Peptide, crh Peptide, zgc:101864 Peptide, CRH Peptide, corticoliberin Peptide, crhb Peptide, crh.1-a Peptide, crha Peptide, corticotropin releasing hormone Peptide, corticotropin releasing hormone b Peptide, corticotropin releasing hormone S homeolog Peptide, corticotropin releasing hormone L homeolog Peptide, Crh Peptide, CRH Peptide, crhb Peptide, crh Peptide, crh.S Peptide, crh.L Peptide
    背景
    Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.

    Alias Symbols: CRF

    Protein Size: 196
    分子量
    21 kDa
    基因ID
    1392
    NCBI登录号
    NM_000756, NP_000747
    UniProt
    P06850
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