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Corticotropin Releasing Hormone (CRH) (C-Term) Peptide

CRH 适用: 人 宿主: 合成 WB, BP
产品编号 ABIN2184150
发货至: 中国

Quick Overview for Corticotropin Releasing Hormone (CRH) (C-Term) Peptide (ABIN2184150)

抗原

CRH (Corticotropin Releasing Hormone (CRH))

宿主

资源

  • 10
合成

应用范围

Western Blotting (WB), Blocking Peptide (BP)
  • 蛋白结构域

    C-Term

    序列

    GGHQEAPERE RRSEEPPISL DLTFHLLREV LEMARAEQLA QQAHSNRKLM

    产品特性

    This is a synthetic peptide designed for use in combination with anti-CRH Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.

    纯化方法

    Purified
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Lyophilized

    溶解方式

    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.

    浓度

    1 mg/mL

    缓冲液

    Final peptide concentration is 1 mg/mL in PBS.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原

    CRH (Corticotropin Releasing Hormone (CRH))

    背景

    Corticotropin-releasing hormone is secreted by the paraventricular nucleus (PVN) of the hypothalamus in response to stress. Marked reduction in this protein has been observed in association with Alzheimer disease and autosomal recessive hypothalamic corticotropin deficiency has multiple and potentially fatal metabolic consequences including hypoglycemia and hepatitis. In addition to production in the hypothalamus, this protein is also synthesized in peripheral tissues, such as T lymphocytes and is highly expressed in the placenta. In the placenta it is a marker that determines the length of gestation and the timing of parturition and delivery. A rapid increase in circulating levels of the hormone occurs at the onset of parturition, suggesting that, in addition to its metabolic functions, this protein may act as a trigger for parturition.

    Alias Symbols: CRF

    Protein Size: 196

    分子量

    21 kDa

    基因ID

    1392

    NCBI登录号

    NM_000756, NP_000747

    UniProt

    P06850
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