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Tumor Susceptibility Gene 101 (TSG101) (N-Term) Peptide

TSG101 适用: 人 宿主: 合成 BP, WB
产品编号 ABIN2183454
发货至: 中国
  • 抗原 See all TSG101 products
    TSG101 (Tumor Susceptibility Gene 101 (TSG101))
    蛋白结构域
    N-Term
    宿主
    资源
    • 8
    合成
    应用范围
    Blocking Peptide (BP), Western Blotting (WB)
    序列
    YKYRDLTVRE TVNVITLYKD LKPVLDSYVF NDGSSRELMN LTGTIPVPYR
    产品特性
    This is a synthetic peptide designed for use in combination with anti-TSG101 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
    纯化方法
    Purified
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Lyophilized
    溶解方式
    Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
    浓度
    1 mg/mL
    缓冲液
    Final peptide concentration is 1 mg/mL in PBS.
    注意事项
    Avoid repeat freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
  • 抗原
    TSG101 (Tumor Susceptibility Gene 101 (TSG101))
    别名
    CG9712 Peptide, DmTSG101 Peptide, Dmel\\CG9712 Peptide, ESCRT-I Peptide, Tsg101 Peptide, burs Peptide, dTSg101 Peptide, dTsg101 Peptide, dVps23 Peptide, ept Peptide, tsg101 Peptide, vps23 Peptide, TSG101 Peptide, MGC76193 Peptide, TSG10 Peptide, VPS23 Peptide, AI255943 Peptide, CC2 Peptide, Rw Peptide, zgc:86926 Peptide, tumor susceptibility 101 Peptide, Tumor susceptibility gene 101 Peptide, Tumor Susceptibility Gene homolog Peptide, tumor susceptibility gene 101 Peptide, tumor susceptibility 101a Peptide, tumor susceptibility 101 L homeolog Peptide, TSG101 Peptide, tsg-101 Peptide, tsg101 Peptide, Tsg101 Peptide, tsg101a Peptide, tsg101.L Peptide
    背景
    The protein encoded by this gene belongs to a group of apparently inactive homologs of ubiquitin-conjugating enzymes. The gene product contains a coiled-coil domain that interacts with stathmin, a cytosolic phosphoprotein implicated in tumorigenesis. The protein may play a role in cell growth and differentiation and act as a negative growth regulator. In vitro steady-state expression of this tumor susceptibility gene appears to be important for maintenance of genomic stability and cell cycle regulation. Mutations and alternative splicing in this gene occur in high frequency in breast cancer and suggest that defects occur during breast cancer tumorigenesis and/or progression.

    Alias Symbols: TSG10, VPS23

    Protein Size: 390
    分子量
    44 kDa
    基因ID
    7251
    NCBI登录号
    NM_006292, NP_006283
    UniProt
    Q99816
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