Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (C-Term) Peptide
CASP10
适用: 人
宿主: 合成
BP, WB
产品编号 ABIN2183407
发货至:
中国
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Contact Info
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中国
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北京 101111
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Quick Overview for Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10) (C-Term) Peptide (ABIN2183407)
抗原
Caspase 10 (CASP10)
(Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
宿主
人
资源
合成
应用范围
Blocking Peptide (BP), Western Blotting (WB)
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蛋白结构域
- C-Term
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序列
- QSLCNHLKKL VPRHEDILSI LTAVNDDVSR RVDKQGTKKQ MPQPAFTLRK
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产品特性
- This is a synthetic peptide designed for use in combination with anti-CASP10 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
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背景
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This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer.
Alias Symbols: ALPS2, FLICE2, MCH4
Protein Size: 522 -
分子量
- 57 kDa
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基因ID
- 843
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NCBI登录号
- NM_032977, NP_116759
抗原
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