Ring Finger Protein 213 (RNF213) (N-Term) Peptide
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北京 101111
Quick Overview for Ring Finger Protein 213 (RNF213) (N-Term) Peptide (ABIN2183223)
抗原
宿主
资源
应用范围
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蛋白结构域
- N-Term
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序列
- ETGNNSVQTV FQGTLAATKR WLREVFTKNM LTSSGASFTY VKEIEVWRRL
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产品特性
- This is a synthetic peptide designed for use in combination with anti-RNF213 Antibody. It may block above mentioned antibody from binding to its target protein in western blot and/or immunohistochecmistry under proper experimental settings. There is no guarantee for its use in other applications.
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纯化方法
- Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Lyophilized
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溶解方式
- Add 100 μL of sterile PBS. Final peptide concentration is 1 mg/mL in PBS.
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浓度
- 1 mg/mL
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缓冲液
- Final peptide concentration is 1 mg/mL in PBS.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For longer periods of storage, store at -20°C. Avoid repeat freeze-thaw cycles.
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- RNF213 (Ring Finger Protein 213 (RNF213))
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背景
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This gene encodes a protein containing a C3HC4-type RING finger domain, which is a specialized type of Zn-finger that binds two atoms of zinc and is thought to be involved in mediating protein-protein interactions. The protein also contains an AAA domain, which is associated with ATPase activity. This gene is a susceptibility gene for Moyamoya disease, a vascular disorder of intracranial arteries. This gene is also a translocation partner in anaplastic large cell lymphoma and inflammatory myofibroblastic tumor cases, where a t(2,17)(p23,q25) translocation has been identified with the anaplastic lymphoma kinase (ALK) gene on chromosome 2, and a t(8,17)(q24,q25) translocation has been identified with the MYC gene on chromosome 8.
Alias Symbols: -
Protein Size: 1063 -
分子量
- 118 kDa
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基因ID
- 57674
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NCBI登录号
- NM_020954, NP_066005
抗原
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